By Shein-Chung Chow

In scientific trial perform, debatable statistical matters unavoidably take place whatever the compliance with reliable statistical perform and solid scientific perform. yet by way of deciding on the explanations of the problems and correcting them, the research targets of scientific trials will be larger completed. Controversial Statistical matters in medical Trials covers as a rule encountered arguable statistical matters in medical trials and, every time attainable, makes options to solve those problems.



The booklet specializes in matters happening at a number of levels of medical learn and improvement, together with early-phase scientific improvement (such as bioavailability/bioequivalence), bench-to-bedside translational examine, and late-phase scientific improvement. a number of examples illustrate the impression of those matters at the overview of the protection and efficacy of the try remedy lower than research. the writer additionally bargains strategies relating to attainable resolutions of the problems.



Written through one of many preeminent specialists within the box, this booklet presents an invaluable table reference and state-of-the paintings exam of complicated matters in scientific trials for scientists within the pharmaceutical undefined, medical/statistical reviewers in executive regulatory businesses, and researchers and scholars in academia.

Show description

Read or Download Controversial Statistical Issues in Clinical Trials (Chapman & Hall/CRC Biostatistics Series) PDF

Similar medical research books

Principles and Practice of Clinical Trial Medicine

Scientific trials are a tremendous a part of medication and healthcare this present day, determining which remedies we use to regard sufferers. a person taken with healthcare at the present time needs to understand the fundamentals of working and studying scientific trial facts. Written in an easy-to-understand kind by way of authors who've huge services and event in either academia and undefined, ideas and perform of scientific Trial drugs covers all the fundamentals of medical trials, from felony and moral concerns to statistical data, to sufferer recruitment and reporting effects.

La médecine sans médecin ? Le numérique au service du malade (Le Débat) (French Edition)

L’évolution accélérée des applied sciences bouleverse l. a. médecine et notre système sanitaire. Elle porte à ses dernières conséquences le changement que le stéthoscope de Laennec avait jadis engagé en forgeant un software qui démultiplie le pouvoir de l’observation. Nous assistons pour de bon à l’émergence de ce que man Vallancien suggest d’appeler une "média-médecine", une médecine médiatisée par le recours aux capacités de l’ordinateur, que l’on retrouve de l. a. génétique à l. a. robotique chirurgicale, en passant par l. a. télémédecine et les communautés de malades.

Managing the Laboratory Animal Facility, Third Edition

Compliment for the former Editions"The writer brings in administration knowledge from the realm open air laboratory animal drugs and veterinary medication. therefore, there's a wealthy mix of the event of a pro specialist and the theoretical framework utilized by colleges of administration …. i like to recommend this e-book to managers and laboratory animal experts at any degree in their careers.

Extra info for Controversial Statistical Issues in Clinical Trials (Chapman & Hall/CRC Biostatistics Series)

Sample text

Download PDF sample

Rated 4.50 of 5 – based on 27 votes